Skin Enriching Lipogrid® Technology has been designed to control release and penetrate deep.
Fluorescent microscopy shows the lipids in Lipogrid® Technology penetrate beyond the stratum corneum (SC) into the epidermis (E)
The ingredients are designed to Hydrate, Repair and Protect
What are the key ingredients of Skin Enriching Lipogrid® Technology?
The physiological lipids in Skin Enriching Lipogrid® Technology are Ceramides, hydrogenated Phosphatidylcholine, cholesterol, and Palmitic acid, lipids occurring naturally in the human body and skin. These lipids penetrate deep to help Hydrate, Protect and Repair skin layer.
- A humectant
- Attracts moisture to the skin
- Softens skin and improves elasticity
- Silicone oil
- Protects the skin by forming a barrier that prevents moisture loss
- Dimethicone molecules are too large to physically pass through the upper cells of the skin
- Dislikes both the water and proteins inside cells of the skin
- Forms a barrier layer on the skin which must be renewed on a regular basis
Skin Enriching Lipogrid® Technology in Action
In a clinical study conducted by Joseph Fowler, MD, 31 patients were randomized to receive either Ceramax™ (Lipogrid® Technology) or a comparator (ointment or lotion) at the baseline visit. Each patient received Ceramax™ for a 3-week period followed by comparator or vice versa. There was a 2-week washout between study phases.
Patients who received Ceramax™ exhibited consistent improvement in the areas of erythema, scaling, cracking, fissuring, and vesicles.
Patients who received Ceramax™ showed significant improvement in erythema and cracking vs comparator groups.
Individuals who received Ceramax™ were 3-fold more likely to stop concomitant use of steroids vs comparator groups.
52% of patients who received Ceramax™ were able to stop or reduce their steroid use.
Ceramax™ was preferred by 71% of patients vs 29% for comparators.
Ceramax™ received an excellent rating from most patients in all characteristics.
References: 1. Silvander M, Ringstad L, Ghadially R, Sköld T. A New Topical Formulation Concept with Lipids that Mimics Skin Composition. Data on file. 2. Fowler JF, Perryman JH. A Comparator Study of an Adjunctive Dermal Lipid Replacement in the Management of Refractory Hand Contact Dermatitis. Data on file.